IGF-1 levels in Patients with Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (Type DM) is a metabolic disorder group with mechanisms that include hyperglycemia, insulin resistance and hyperinsulinemia. DM has close association IGF-1, where the active form of IGF-1 becomes elevated by reason fact hyperinsulinemia inhibits production IGF-binding proteins (IGFBP) 1/IGFBP 2. The ability to promote cell proliferation inhibit apoptosis, hence one risk factors for cancer growth. This was an analytical study conducted in August at Harapan Bunda Clinic, Medan, Indonesia determine difference between level blood glucose type patients different age groups. Twenty subjects participated this were divided based on their into 35-50 years old or Group 1 51-65 year levels both groups compared analyzed using T-test dependent method. Results showed higher (35-50 old) when significant. change diabetic cannot be determined only sugar level.